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Avian sarcoma and leukosis virus pol-endonuclease recognition of the tandem long terminal repeat junction: minimum site required for cleavage is also required for viral growth.

Integration of retroviral DNA is a site-specific reaction involving an endonuclease encoded by the viral pol gene (pol-endo). In vitro the pol-endo from avian sarcoma and leukosis viruses (ASLVs) cleaves both DNA strands near the U5-U3 junction of tandem long terminal repeats (LTR-LTR junction) in s...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Cobrinik, D, Katz, R, Terry, R, Skalka, A M, Leis, J
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1987
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254209/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3033327/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.6.1999-2008.1987
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