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The membrane-binding domain and myristylation of p60v-src are not essential for stimulation of cell proliferation.

Previous studies showed that the amino-terminal domain of Rous sarcoma virus p60v-src involved in myristylation and membrane association of the protein is required for morphological transformation and anchorage independence. Analysis of src delection mutants revealed that the amino-terminal one-thir...

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Detalles Bibliográficos
Publicado en:J Virol
Principais autores: Calothy, G, Laugier, D, Cross, F R, Jove, R, Hanafusa, T, Hanafusa, H
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology (ASM) 1987
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254154/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3106650/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.5.1678-1681.1987
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