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Congruent Docking of Dimeric Kinesin and ncd into Three-dimensional Electron Cryomicroscopy Maps of Microtubule–Motor ADP Complexes

We present a new map showing dimeric kinesin bound to microtubules in the presence of ADP that was obtained by electron cryomicroscopy and image reconstruction. The directly bound monomer (first head) shows a different conformation from one in the more tightly bound empty state. This change in the f...

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Main Authors: Hirose, Keiko, Löwe, Jan, Alonso, Maria, Cross, Robert A., Amos, Linda A.
Format: Artigo
Jezik:Inglês
Izdano: The American Society for Cell Biology 1999
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC25414/
https://ncbi.nlm.nih.gov/pubmed/10359615
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