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Lymphoid cells in the spleens of woodchuck hepatitis virus-infected woodchucks are a site of active viral replication.

Lymphoid cells were purified from the spleens of 15 woodchucks and examined for the presence of woodchuck hepatitis virus (WHV). Lymphoid cells from the spleens of eight of eight chronically infected animals contained high levels of WHV RNA and DNA. A 100-fold lower level of WHV DNA was found in the...

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Bibliographic Details
Published in:J Virol
Main Authors: Korba, B E, Wells, F, Tennant, B C, Cote, P J, Gerin, J L
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1987
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254105/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3573141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.5.1318-1324.1987
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