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Selective synthesis and secretion of particles composed of the hepatitis B virus middle surface protein directed by a recombinant vaccinia virus: induction of antibodies to pre-S and S epitopes.

Selective synthesis in mammalian cells of the hepatitis B virus middle surface (MS) protein, which is 55 amino acids longer than the major surface (S) protein, was achieved by using a recombinant vaccinia virus. The 33-kilodalton MS polypeptide was glycosylated and secreted as particles that resembl...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Cheng, K C, Moss, B
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1987
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254096/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2434666/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.4.1286-1290.1987
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