Murine cells carrying integrated tandem genomes of hepatitis B virus DNA transcribe RNAs from endogenous promoters on both viral strands and express middle and major viral envelope proteins.

Clone 4.10 cells were isolated as a methotrexate-resistant clone arising after cotransfection of mouse 3T3 cells with plasmid DNA containing a head-to-tail dimer of the hepatitis B virus (HBV) genome and DNA coding for methotrexate-resistant dihydrofolate reductase. The majority of methotrexate-resi...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Zelent, A Z, Sells, M A, Price, P M, Mohamad, A, Acs, G, Christman, J K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1987
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254071/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3029405/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.4.1108-1115.1987
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