Expression of the Recessive Glomerulosclerosis Gene Mpv17 Regulates MMP-2 Expression in Fibroblasts, the Kidney, and the Inner Ear of Mice

The recessive mouse mutant Mpv17 is characterized by the development of early-onset glomerulosclerosis, concomitant hypertension, and structural alterations of the inner ear. The primary cause of the disease is the loss of function of the Mpv17 protein, a peroxisomal gene product involved in reactiv...

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Main Authors: Reuter, Alexander, Nestl, Andrea, Zwacka, Ralf M., Tuckermann, Jan, Waldherr, Rüdiger, Wagner, Eva-Maria, Höyhtyä, Matti, zum Gottesberge, Angela M. Meyer, Angel, Peter, Weiher, Hans
Format: Artigo
Language:Inglês
Published: The American Society for Cell Biology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC25405/
https://ncbi.nlm.nih.gov/pubmed/9658163
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