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Instability of large direct repeats in retrovirus vectors.

Retrovirus vectors were constructed with large (0.85- to 1.3-kilobase-pair) direct repeats in their genomes. Deletions involving the direct repeats occurred at a high frequency. Deletions occurred both when the direct repeats were in tandem and when they were separated by additional sequences. These...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Rhode, B W, Emerman, M, Temin, H M
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 1987
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC254040/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3806800/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.3.925-927.1987
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