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Disease specificity of nondefective Friend and Moloney murine leukemia viruses is controlled by a small number of nucleotides.

Moloney murine leukemia virus induces T cell lymphomas after injection into NFS mice, whereas the nondefective Friend virus induces erythroleukemias. Previous studies showed that sequences encompassing the viral transcriptional signals in U3 are the primary determinant of this phenotype in recombina...

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Autors principals: Li, Y, Golemis, E, Hartley, J W, Hopkins, N
Format: Artigo
Idioma:Inglês
Publicat: 1987
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC254008/
https://ncbi.nlm.nih.gov/pubmed/3468264
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