A single-base change within the DNA polymerase locus of herpes simplex virus type 2 can confer resistance to aphidicolin.
An aphidicolin-resistant (Aphr) mutant of herpes simplex virus (HSV) type 2 strain 186 previously has been shown to induce an altered viral DNA polymerase that is more resistant to aphidicolin and more sensitive to phosphonoacetic acid (PAA) than is wild-type DNA polymerase. In this study the mutati...
Gespeichert in:
| Veröffentlicht in: | J Virol |
|---|---|
| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Society for Microbiology (ASM)
1987
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253961/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3027369/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.61.2.388-394.1987 |
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