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Anion and Cation Mixed-Bed Ion Exchange for Enhanced Multidimensional Separations of Peptides and Phosphopeptides
Shotgun proteomics typically uses multidimensional LC/MS/MS analysis of enzymatically digested proteins, where strong cation-exchange (SCX) and reversed-phase (RP) separations are coupled to increase the separation power and dynamic range of analysis. Here we report an on-line multidimensional LC me...
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Main Authors: | , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado: |
2007
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Assuntos: | |
Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538959/ https://ncbi.nlm.nih.gov/pubmed/17411013 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ac062292d |
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