Stimulation of peroxynitrite catalysis improves insulin sensitivity in high fat diet-fed mice

Peroxynitrite synthesis is increased in insulin resistant animals and humans. Peroxynitirite-induced nitration of insulin signalling proteins impairs insulin action in vitro, but the role of peroxynitrite in the pathogenesis of insulin resistance in vivo is not known. We therefore assessed the effec...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Duplain, Hervé, Sartori, Claudio, Dessen, Pierre, Jayet, Pierre-Yves, Schwab, Marcos, Bloch, Jonathan, Nicod, Pascal, Scherrer, Urs
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Blackwell Science Inc 2008
Pynciau:
Integrative
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538923/
https://ncbi.nlm.nih.gov/pubmed/18591189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.154302
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