A causal role for ERG in neoplastic transformation of prostate epithelium

A significant proportion of human prostate cancers carry a chromosomal rearrangement resulting in the overexpression of the ETS transcription factor, ERG; however, the functional significance of this event is poorly understood. We report here that up-regulation of ERG transcript is sufficient for th...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Klezovitch, Olga, Risk, Michael, Coleman, Ilsa, Lucas, Jared M., Null, Manda, True, Lawrence D., Nelson, Peter S., Vasioukhin, Valeri
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2008
Pynciau:
Biological Sciences
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538886/
https://ncbi.nlm.nih.gov/pubmed/18245377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711711105
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