The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development

The vacuolated lens (vl) mouse mutant causes congenital cataracts and neural tube defects (NTDs), with the NTDs being caused by abnormal neural fold apposition and fusion. Our positional cloning of vl indicates these phenotypes result from a deletion mutation in an uncharacterized orphan G protein-c...

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Hlavní autoři: Matteson, Paul G., Desai, Jigar, Korstanje, Ron, Lazar, Gloria, Borsuk, Tanya E., Rollins, Jarod, Kadambi, Sindhuja, Joseph, Jamie, Rahman, Taslima, Wink, Jason, Benayed, Rym, Paigen, Beverly, Millonig, James H.
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2008
Témata:
Biological Sciences
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538885/
https://ncbi.nlm.nih.gov/pubmed/18250320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705657105
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