The orphan G protein-coupled receptor, Gpr161, encodes the vacuolated lens locus and controls neurulation and lens development

The vacuolated lens (vl) mouse mutant causes congenital cataracts and neural tube defects (NTDs), with the NTDs being caused by abnormal neural fold apposition and fusion. Our positional cloning of vl indicates these phenotypes result from a deletion mutation in an uncharacterized orphan G protein-c...

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Detaylı Bibliyografya
Asıl Yazarlar: Matteson, Paul G., Desai, Jigar, Korstanje, Ron, Lazar, Gloria, Borsuk, Tanya E., Rollins, Jarod, Kadambi, Sindhuja, Joseph, Jamie, Rahman, Taslima, Wink, Jason, Benayed, Rym, Paigen, Beverly, Millonig, James H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2008
Konular:
Biological Sciences
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538885/
https://ncbi.nlm.nih.gov/pubmed/18250320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0705657105
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