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Adaptations of Trypanosoma brucei to gradual loss of kinetoplast DNA: Trypanosoma equiperdum and Trypanosoma evansi are petite mutants of T. brucei

Trypanosoma brucei is a kinetoplastid flagellate, the agent of human sleeping sickness and ruminant nagana in Africa. Kinetoplastid flagellates contain their eponym kinetoplast DNA (kDNA), consisting of two types of interlocked circular DNA molecules: scores of maxicircles and thousands of minicircl...

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Detalhes bibliográficos
Main Authors: Lai, De-Hua, Hashimi, Hassan, Lun, Zhao-Rong, Ayala, Francisco J., Lukeš, Julius
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538871/
https://ncbi.nlm.nih.gov/pubmed/18245376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711799105
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