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Cytoplasmic BK(Ca) channel intron-containing mRNAs contribute to the intrinsic excitability of hippocampal neurons
High single-channel conductance K(+) channels, which respond jointly to membrane depolarization and micromolar concentrations of intracellular Ca(2+) ions, arise from extensive cell-specific alternative splicing of pore-forming α-subunit mRNAs. Here, we report the discovery of an endogenous BK(Ca) c...
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| Auteurs principaux: | , , , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538856/ https://ncbi.nlm.nih.gov/pubmed/18250327 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0711796105 |
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