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Assessing the physiological concentration and targets of nitric oxide in brain tissue
Low nanomolar concentrations of nitric oxide activate guanylyl cyclase to produce cGMP, which has diverse physiological effects. Higher concentrations inhibit mitochondrial respiration at cytochrome c oxidase and this has been proposed to be important physiologically, increasing oxygen permeation in...
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Formato: | Artigo |
Idioma: | Inglês |
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Blackwell Science Inc
2008
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Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538835/ https://ncbi.nlm.nih.gov/pubmed/18535091 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.154724 |
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