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Mouse models of human KCNQ2 and KCNQ3 mutations for benign familial neonatal convulsions show seizures and neuronal plasticity without synaptic reorganization

The childhood epilepsy syndrome of benign familial neonatal convulsions (BFNC) exhibits the remarkable feature of clinical remission within a few weeks of onset and a favourable prognosis, sparing cognitive abilities despite persistent expression of the mutant KCNQ2 or KCNQ3 potassium channels throu...

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Bibliografski detalji
Glavni autori: Singh, Nanda A, Otto, James F, Jill Dahle, E, Pappas, Chris, Leslie, Jonathan D, Vilaythong, Alex, Noebels, Jeffrey L, Steve White, H, Wilcox, Karen S, Leppert, Mark F
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538806/
https://ncbi.nlm.nih.gov/pubmed/18483067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2008.154971
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