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Mechanisms of augmented vasoconstriction induced by 5-hydroxytryptamine in aortic rings from spontaneously hypertensive rats

BACKGROUND AND PURPOSE: To test whether development of enhanced vasoconstriction to 5-hydroxytryptamine (5-HT; serotonin) in SHR was temporally related to hypertension, elevated vascular superoxide (O(2)(−)) levels, decreased NO bioavailability, or increased contractile effects of cyclooxygenase or...

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Autores principales: Budzyn, K, Ravi, R M, Miller, A A, Sobey, C G
Formato: Artigo
Lenguaje:Inglês
Publicado: Nature Publishing Group 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538692/
https://ncbi.nlm.nih.gov/pubmed/18552867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjp.2008.247
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