Direct correlation between a negative autoregulatory response element at the cap site of the herpes simplex virus type 1 IE175 (alpha 4) promoter and a specific binding site for the IE175 (ICP4) protein.

In transient-expression assays, the IE175 (alpha 4) promoter region of herpes simple virus is down-regulated after cotransfection with DNA encoding its own protein product (IE175 or ICP4). The inhibition by IE175 proved to be highly specific for its own promoter region and did not act on either the...

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Pubblicato in:	J Virol
Autori principali:	Roberts, M S, Boundy, A, O'Hare, P, Pizzorno, M C, Ciufo, D M, Hayward, G S
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1988
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253866/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845144/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.11.4307-4320.1988
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