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Lipid-rhodopsin hydrophobic mismatch alters rhodopsin helical content

The ability of photo-activated rhodopsin to achieve the enzymatically active metarhodopsin II conformation is exquisitely sensitive to bilayer hydrophobic thickness. The sensitivity of rhodopsin to the lipid matrix has been explained by the hydrophobic matching theory which predicts that lipid bilay...

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Hlavní autoři: Soubias, Olivier, Niu, Shui-Lin, Mitchell, Drake C., Gawrisch, Klaus
Médium: Artigo
Jazyk:Inglês
Vydáno: 2008
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538621/
https://ncbi.nlm.nih.gov/pubmed/18712874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803599x
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