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Lipid-rhodopsin hydrophobic mismatch alters rhodopsin helical content

The ability of photo-activated rhodopsin to achieve the enzymatically active metarhodopsin II conformation is exquisitely sensitive to bilayer hydrophobic thickness. The sensitivity of rhodopsin to the lipid matrix has been explained by the hydrophobic matching theory which predicts that lipid bilay...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Soubias, Olivier, Niu, Shui-Lin, Mitchell, Drake C., Gawrisch, Klaus
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538621/
https://ncbi.nlm.nih.gov/pubmed/18712874
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja803599x
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