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Successful Inhibition of Tumor Development by Specific Class-3 Semaphorins Is Associated with Expression of Appropriate Semaphorin Receptors by Tumor Cells

The class-3 semaphorins (sema3s) include seven family members. Six of them bind to neuropilin-1 (np1) or neuropilin-2 (np2) receptors or to both, while the seventh, sema3E, binds to the plexin-D1 receptor. Sema3B and sema3F were previously characterized as tumor suppressors and as inhibitors of tumo...

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Autori principali: Kigel, Boaz, Varshavsky, Asya, Kessler, Ofra, Neufeld, Gera
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2008
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2538586/
https://ncbi.nlm.nih.gov/pubmed/18818766
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0003287
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