Replication of simian virus 40 DNA after UV irradiation: evidence of growing fork blockage and single-stranded gaps in daughter strands.

The molecular mechanisms of in vivo inhibition of mammalian DNA replication by exposure to UV light (at 254 nm) was studied in monkey and human cells infected with simian virus 40. Analysis of viral DNA by electron microscopy and sucrose gradients confirmed that the presence of UV-induced lesions se...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Mezzina, M, Menck, C F, Courtin, P, Sarasin, A
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253858/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845136/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.11.4249-4258.1988
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