Structural analysis of a hepatitis B virus genome integrated into chromosome 17p of a human hepatocellular carcinoma.

Hepatitis B virus (HBV) is clearly a factor in the development of hepatocellular carcinoma, but its mechanism of action remains obscure. One possibility is that the HBV integration event alters the expression of a nearby growth-regulatory cellular gene. A 9-kilobase (kb) DNA fragment containing an H...

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Detalhes bibliográficos
Main Authors: Zhou, Y Z, Slagle, B L, Donehower, L A, vanTuinen, P, Ledbetter, D H, Butel, J S
Formato: Artigo
Idioma:Inglês
Publicado em: 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC253855/
https://ncbi.nlm.nih.gov/pubmed/2845134
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