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Restricted replication of hepatitis A virus in cell culture: encapsidation of viral RNA depletes the pool of RNA available for replication.

The replication of hepatitis A virus (HAV) in BS-C-1 cells was examined under single-cycle growth conditions by using strand-specific probes for detection of viral RNA species. No measurable lag phase was demonstrated between accumulation of positive-strand HAV RNA and production of infectious virio...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Anderson, D A, Ross, B C, Locarnini, S A
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253852/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845131/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.11.4201-4206.1988
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