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Neutralizing antibodies to an immunodominant envelope sequence do not prevent gp120 binding to CD4.

Animals immunized with the human immunodeficiency virus type 1 gp160 glycoprotein or certain recombinant envelope components develop potent virus-neutralizing activity. This activity is principally due to antibodies directed toward a hypervariable region of gp120 between cysteine residues 302 and 33...

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Bibliographic Details
Main Authors: Skinner, M A, Langlois, A J, McDanal, C B, McDougal, J S, Bolognesi, D P, Matthews, T J
Format: Artigo
Language:Inglês
Published: 1988
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC253851/
https://ncbi.nlm.nih.gov/pubmed/2845130
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