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The Catalytic Mn(2+) Sites in the Enolase-Inhibitor Complex - Crystallography, Single Crystal EPR and DFT Calculations
Crystals of Zn(2+) / Mn(2+) yeast enolase with the inhibitor PhAH (phosphonoacetohydroxamate) were grown under conditions with a slight preference for binding of Zn(2+) at the higher affinity site, site I. The structure of the Zn(2+)/Mn(2+) PhAH complex was solved at a resolution of 1.54 Å and the t...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2538446/ https://ncbi.nlm.nih.gov/pubmed/17367133 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja066124e |
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