A tagged helper-free Friend virus causes clonal erythroblast immortality by specific proviral integration in the cellular genome.
A colinear molecular clone of the Lilly-Steeves polycythemia strain of Friend spleen focus-forming virus (SFFV) was modified by inserting a 215-base-pair tag of simian virus 40 DNA into its nonfunctional pol gene region. The DNA was then transfected into psi-2 packaging cells, and helper-free tagged...
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| Published in: | J Virol |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
American Society for Microbiology (ASM)
1988
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253844/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845127/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.11.4129-4135.1988 |
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