Isolation of poliovirus 2C mutants defective in viral RNA synthesis.

Two poliovirus mutants were isolated that contain an oligonucleotide linker insertion in the 2C-coding region of the viral genome. One, 2C-31, has a strongly temperature-sensitive phenotype and the other, 2C-32, forms small plaques on HeLa cell monolayers at all temperatures. Both mutants have a sev...

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Vydáno v:	J Virol
Hlavní autoři:	Li, J P, Baltimore, D
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology (ASM) 1988
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253830/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2845120/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.11.4016-4021.1988
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