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PPPYEPTAP Motif Is the Late Domain of Human T-Cell Leukemia Virus Type 1 Gag and Mediates Its Functional Interaction with Cellular Proteins Nedd4 and Tsg101

The human T-cell leukemia virus type 1 (HTLV-1) Gag polyprotein contains two adjacent proline-rich motifs (sequence PPPYEPTAP) in the C terminus of the matrix domain. Proline-to-alanine mutations were introduced into either or both motifs of HTLV-1 to determine the effect on the release of HTLV-1 vi...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Bouamr, Fadila, Melillo, Jessica A., Wang, Margaret Q., Nagashima, Kunio, de Los Santos, Martha, Rein, Alan, Goff, Stephen P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253756/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14581525/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/JVI.77.22.11882-11895.2003
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