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The gene encoding the nonstructural protein of B19 (human) parvovirus may be lethal in transfected cells.

The B19 parvovirus is a cause of bone marrow failure in humans. B19 is toxic to erythroid progenitor cells in vitro. Viral products possibly responsible for toxicity were explored by transfection of cloned B19 genome into HeLa cells. The nonstructural (NS) protein was detected in cells 30 h after tr...

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Detalhes bibliográficos
Publicado no:J Virol
Principais autores: Ozawa, K, Ayub, J, Kajigaya, S, Shimada, T, Young, N
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253725/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2969055/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.8.2884-2889.1988
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