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Cooperative Function of Tbx1 and Brn4 in the Periotic Mesenchyme is Necessary for Cochlea Formation

The T-box transcription factor TBX1 has been identified as the major gene responsible for the etiology of velocardiofacial syndrome/DiGeorge syndrome (VCFS/DGS). Conductive hearing loss occurs in a majority of patients with this syndrome, while sensorineural deafness has also been reported in some c...

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Detalhes bibliográficos
Main Authors: Braunstein, Evan M., Crenshaw III, E. Bryan, Morrow, Bernice E., Adams, Joe C.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536808/
https://ncbi.nlm.nih.gov/pubmed/18231833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10162-008-0110-6
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