Differences in activity and phosphorylation of MAPK enzymes in esophageal squamous cells of GERD patients with and without Barrett's esophagus

We hypothesized that, in esophageal squamous epithelial cells, there are differences among individuals in the signal transduction pathways activated by acid reflux that might underlie the development of Barrett's esophagus. To explore that hypothesis, we immortalized nonneoplastic, esophageal s...

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Autores principales: Zhang, Hui Ying, Zhang, Xi, Chen, Xi, Thomas, Deena, Hormi-Carver, Kathy, Elder, Frederick, Spechler, Stuart J., Souza, Rhonda F.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2008
Materias:
Mucosal Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536777/
https://ncbi.nlm.nih.gov/pubmed/18617556
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.90262.2008
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