Effects of hyperinsulinemia on hepatic metalloproteinases and their tissue inhibitors

To gain insight into the pathogenesis of hepatic fibrosis related to insulin resistance, we have examined the effects of euglycemic hyperinsulinemia on three matrix metalloproteinases (MMP-2, MMP-9, and MT1-MMP) and on two major tissue inhibitors of MMPs (TIMP-1 and TIMP-2) in liver of insulin-sensi...

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Bibliographic Details
Main Authors: Boden , Guenther, Song, Weiwei, Kresge, Karen, Mozzoli, Maria, Cheung, Peter
Format: Artigo
Language:Inglês
Published: American Physiological Society 2008
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536734/
https://ncbi.nlm.nih.gov/pubmed/18664596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.90370.2008
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