Osteopontin Promoter Polymorphism is Associated with Increased Carotid Intima-Media Thickness

BACKGROUND: Osteopontin (OPN)-transgenic mice exhibit increased carotid artery intima-media thickness (CIMT), smooth muscle cell proliferation, and atheroma formation. METHODS: An association of the human T-66G promoter variant with CIMT was examined in Caucasian adults grouped according to metaboli...

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Main Authors: de las Fuentes, Lisa, Gu, C. Charles, Mathews, Santhosh J., Reagan, Joann L., Ruthmann, Nicholas P., Waggoner, Alan D., Lai, Chung-Fang, Towler, Dwight A., Dávila-Román, Víctor G.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536614/
https://ncbi.nlm.nih.gov/pubmed/18406574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.echo.2008.02.005
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