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Screening procedure using chicks infected with the sporozoites of Plasmodium gallinaceum in an antimalarial drug development programme

Of 10 000 compounds tested for tissue schizontocidal activity in a Plasmodium gallinaceum—chick model, 157 were also tested in a definitive mouse test (DMT) and 277 in a rhesus monkey test (RMT). The results in the avian model were 78% and 55% in agreement with those of the DMT and RMT, respectively...

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Detalhes bibliográficos
Main Authors: Kinnamon, Kenneth E., Davidson, David E., Rane, Dora S.
Formato: Artigo
Idioma:Inglês
Publicado em: 1985
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536355/
https://ncbi.nlm.nih.gov/pubmed/3872730
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