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Plasma concentrations of pyrimethamine and sulfadoxine and evaluation of pharmaco-kinetic data by computerized curve fitting

For the determination of the plasma concentration profiles of pyrimethamine and sulfadoxine after the administration of 1 tablet of Fansidar, highly specific analytical methods are needed as the pyrimethamine concentration is low (0.2 - 0.02 mg/litre) and the concentration ratio of the two component...

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Detalles Bibliográficos
Main Authors: Weidekamm, E., Plozza-Nottebrock, H., Forgo, I., Dubach, U. C.
Formato: Artigo
Idioma:Inglês
Publicado: 1982
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2536029/
https://ncbi.nlm.nih.gov/pubmed/6979415
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