Two specific topoisomerase II inhibitors prevent replication of human cytomegalovirus DNA: an implied role in replication of the viral genome.

In this study, we show that human cytomegalovirus DNA synthesis is inhibited in infected confluent human embryonic lung cells treated with the DNA-intercalative topoisomerase II inhibitor 4-9'-(acridinylamino)methanesulfon-m-anisidide (m-AMSA). Similar inhibitory effects were observed with VM-26, a...

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Bibliografiske detaljer

Udgivet i:	J Virol
Principais autores:	Benson, J D, Huang, E S
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology (ASM) 1988
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253602/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2846890/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.12.4797-4800.1988
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