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A Weighted-Holm Procedure Accounting for Allele Frequencies in Genomewide Association Studies

In the context of genomewide association studies where hundreds of thousand of polymorphisms are tested, stringent thresholds on the raw association test P-values are generally used to limit false-positive results. Instead of using thresholds based on raw P-values as in Bonferroni and sequential Sid...

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Detalhes bibliográficos
Main Authors: Dalmasso, Cyril, Génin, Emmanuelle, Trégouet, David-Alexandre
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535720/
https://ncbi.nlm.nih.gov/pubmed/18723893
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.089839
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