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Retention of Induced Mutations in a Drosophila Reverse-Genetic Resource

Targeting induced local lesions in genomes (TILLING) is a reverse-genetic method for identifying point mutations in chemically mutagenized populations. For functional genomics, it is ideal to have a stable collection of heavily mutagenized lines that can be screened over an extended period of time....

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Detalhes bibliográficos
Main Authors: Cooper, Jennifer L., Greene, Elizabeth A., Till, Bradley J., Codomo, Christine A., Wakimoto, Barbara T., Henikoff, Steven
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2535715/
https://ncbi.nlm.nih.gov/pubmed/18780737
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.108.092437
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