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Demonstration in vitro of temperature-sensitive elongation of RNA in Sindbis virus mutant ts6.

Characterization of conditionally lethal mutants of alphaviruses, Sindbis virus and Semliki Forest virus, has indicated that in almost all the RNA-negative mutants the temperature-sensitive (ts) defect prevents the formation of active transcription complexes at nonpermissive temperature (40 degrees...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Barton, D J, Sawicki, S G, Sawicki, D L
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253499/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3418782/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.10.3597-3602.1988
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