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Nitrogen-regulated Ubiquitination of the Gap1 Permease of Saccharomyces cerevisiae

Addition of ammonium ions to yeast cells growing on proline as the sole nitrogen source induces rapid inactivation and degradation of the general amino acid permease Gap1 through a process requiring the Npi1/Rsp5 ubiquitin (Ub) ligase. In this study, we show that NH(4)(+) induces endocytosis of Gap1...

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Bibliographische Detailangaben
Hauptverfasser: Springael, Jean-Yves, André, Bruno
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 1998
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC25348/
https://ncbi.nlm.nih.gov/pubmed/9614172
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