Mechanism of c-erbB transduction: newly released transducing viruses retain poly(A) tracts of erbB transcripts and encode C-terminally intact erbB proteins.

We have previously shown that avian leukosis virus (ALV) induces erythroblastosis by insertional activation of the c-erbB gene. In 25% of the ALV-induced leukemic samples we have analyzed, acute retroviruses that have captured the activated erbB oncogene were released. The unusually high frequency a...

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Detalhes bibliográficos
Publicado no:J Virol
Main Authors: Raines, M A, Maihle, N J, Moscovici, C, Crittenden, L, Kung, H J
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 1988
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253402/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2897475/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.7.2437-2443.1988
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