Addition of substitution of simian virus 40 enhancer sequences into the Moloney murine leukemia virus (M-MuLV) long terminal repeat yields infectious M-MuLV with altered biological properties.

Moloney murine leukemia virus (M-MuLV) is a replication-competent retrovirus which induces T-cell lymphoma in mice. The enhancer sequences present within the M-MuLV long terminal repeat (LTR) region of the proviral genome have been shown to influence the disease specificity of the virus strongly. We...

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Vydáno v:J Virol
Hlavní autoři: Hanecak, R, Pattengale, P K, Fan, H
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 1988
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC253401/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2836623/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.62.7.2427-2436.1988
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