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Addition of substitution of simian virus 40 enhancer sequences into the Moloney murine leukemia virus (M-MuLV) long terminal repeat yields infectious M-MuLV with altered biological properties.

Moloney murine leukemia virus (M-MuLV) is a replication-competent retrovirus which induces T-cell lymphoma in mice. The enhancer sequences present within the M-MuLV long terminal repeat (LTR) region of the proviral genome have been shown to influence the disease specificity of the virus strongly. We...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Hanecak, R, Pattengale, P K, Fan, H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 1988
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC253401/
https://ncbi.nlm.nih.gov/pubmed/2836623
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