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Hemoglobin-based O(2) carrier O(2) affinity and capillary inlet pO(2) are important factors that influence O(2) transport in a capillary

Hemopure (Biopure; Cambridge, MA) and PolyHeme (Northfield Laboratories; Evanston, IL) are two acellular hemoglobin-based O(2) carriers (HBOCs) currently in phase III clinical trials for use as red blood cell substitutes. The most common adverse side effect that these HBOCs exhibit is increased vaso...

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Detalhes bibliográficos
Main Authors: Dimino, Michael L., Palmer, Andre F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533853/
https://ncbi.nlm.nih.gov/pubmed/17555329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bp0700298
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