Hypoxia-Inducible Factor Augments Experimental Colitis Through a MIF-Dependent Inflammatory Signaling Cascade

BACKGROUND & AIMS: Colon epithelial cells are critical for barrier function and contain a highly developed immune response. A previous study has shown hypoxia-inducible factor (HIF) as a critical regulator of barrier protection during colon epithelial injury. However, the role of HIF signaling i...

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Detalhes bibliográficos
Main Authors: Shah, Yatrik M, Ito, Shinji, Morimura, Keiichirou, Chen, Chi, Yim, Sun-hee, Haase, Volker H, Gonzalez, Frank J
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533811/
https://ncbi.nlm.nih.gov/pubmed/18439915
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2008.03.009
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