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Collagen Fibril Formation: A NEW TARGET TO LIMIT FIBROSIS
We present a concept for reducing formation of fibrotic deposits by inhibiting self-assembly of collagen molecules into fibrils, a main component of fibrotic lesions. Employing monoclonal antibodies that bind to the telopeptide region of a collagen molecule, we found that blocking telopeptide-mediat...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2533774/ https://ncbi.nlm.nih.gov/pubmed/18650436 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M804272200 |
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