An Arginine to Lysine Mutation in the Vicinity of the Heme Propionates Affects the Redox Potentials of the Hemes and Associated Electron and Proton Transfer in Cytochrome c Oxidase

Cytochrome c oxidase pumps protons across a membrane using energy from electron transfer and reduction of oxygen to water. It is postulated that an element of the energy transduction mechanism is the movement of protons to the vicinity of the hemes upon reduction, to favor charge neutrality. Possibl...

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Bibliographic Details
Main Authors: Mills, Denise A., Geren, Lois, Hiser, Carrie, Schmidt, Bryan, Durham, Bill, Millett, Francis, Ferguson-Miller, Shelagh
Format: Artigo
Language:Inglês
Published: 2005
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533729/
https://ncbi.nlm.nih.gov/pubmed/16060654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi050283d
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