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Role of Linoleic Acid Hydroperoxide Preformed by Cyclooxygenase-1 or -2 on the Regulation of Prostaglandin Formation from Arachidonic Acid by the Respective Enzyme

Linoleic acid (LA) preincubated with cyclooxygenase (COX)-1 or -2 inhibited prostaglandin (PG) formation from arachidonic acid (AA) catalyzed by the respective enzyme, but LA without the preincubation did not. 13S-Hydroperoxy-9Z,11E-octadecadienoic acid (13-HPODE) a hydroperoxy adduct of LA inhibite...

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Detalhes bibliográficos
Main Authors: Fujimoto, Yohko, Yonemura, Toshimitsu, Sakuma, Satoru
Formato: Artigo
Idioma:Inglês
Publicado em: the Society for Free Radical Research Japan 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533720/
https://ncbi.nlm.nih.gov/pubmed/18818754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3164/jcbn.2008047
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