Laparoscopic ileocolic resection versus infliximab treatment of distal ileitis in Crohn's disease: a randomized multicenter trial (LIR!C-trial)

BACKGROUND: With the availability of infliximab, nowadays recurrent Crohn's disease, defined as disease refractory to immunomodulatory agents that has been treated with steroids, is generally treated with infliximab. Infliximab is an effective but expensive treatment and once started it is uncl...

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Main Authors: Eshuis, Emma J, Bemelman, Willem A, van Bodegraven, Ad A, Sprangers, Mirjam AG, Bossuyt, Patrick MM, de Wit, AW Marc van Milligen, Crolla, Rogier MPH, Cahen, Djuna L, Oostenbrug, Liekele E, Sosef, Meindert N, Voorburg, Annet MCJ, Davids, Paul HP, van der Woude, C Janneke, Lange, Johan, Mallant, Rosalie C, Boom, Maarten J, Lieverse, Rob J, van der Zaag, Edwin S, Houben, Martin HMG, Vecht, Juda, Pierik, Robert EGJM, van Ditzhuijsen, Theo JM, Prins, Hubert A, Marsman, Willem A, Stockmann, Henricus B, Brink, Menno A, Consten, Esther CJ, van der Werf, Sjoerd DJ, Marinelli, Andreas WKS, Jansen, Jeroen M, Gerhards, Michael F, Bolwerk, Clemens JM, Stassen, Laurents PS, Spanier, BW Marcel, Bilgen, Ernst Jan Spillenaar, van Berkel, Anne-Marie, Cense, Huib A, van Heukelem, Henk A, van de Laar, Arnold, Slot, Warner Bruins, Eijsbouts, Quirijn A, van Ooteghem, Nancy AM, van Wagensveld, Bart, van den Brande, Jan MH, van Geloven, Anna AW, Bruin, Karien F, Maring, John K, Oldenburg, Bas, van Hillegersberg, Richard, de Jong, Dirk J, Bleichrodt, Robert, van der Peet, Donald L, Dekkers, Pascal EP, Goei, T Hauwy, Stokkers, Pieter CF
格式: Artigo
語言:Inglês
出版: BioMed Central 2008
主題:
Study Protocol
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2533646/
https://ncbi.nlm.nih.gov/pubmed/18721465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2482-8-15
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